Detalhe da pesquisa
1.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Cell
; 185(2): 283-298.e17, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35021065
2.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Cell
; 187(4): 1011-1015, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38364781
3.
Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.
Cell
; 168(5): 789-800.e10, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28235196
4.
IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling.
Nat Immunol
; 19(4): 354-365, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563620
5.
The Ras GTPase-activating-like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL-1ß release via exosomes.
EMBO J
; 42(1): e110780, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36373462
6.
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
Nat Immunol
; 14(1): 72-81, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23202271
7.
Mechanisms of Corticosteroid Resistance in Type 17 Asthma.
J Immunol
; 209(10): 1860-1869, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36426949
8.
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF).
Nat Immunol
; 12(9): 853-60, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822258
9.
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Nat Immunol
; 12(9): 844-52, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822257
10.
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.
Immunity
; 36(5): 821-33, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22608496
11.
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance.
Immunity
; 37(5): 800-12, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142783
12.
IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility.
J Immunol
; 202(5): 1540-1548, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683702
13.
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.
Immunity
; 32(1): 54-66, 2010 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20060329
14.
IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production.
EMBO J
; 32(4): 583-96, 2013 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23376919
15.
Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
Gastroenterology
; 149(7): 1860-1871.e8, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344057
16.
HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization.
J Immunol
; 191(2): 640-9, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23772036
17.
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.
J Exp Med
; 204(5): 1025-36, 2007 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17470642
18.
T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation.
J Immunol
; 187(6): 3155-64, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856933
19.
TRAF4 is crucial for the propagation of ST2+ memory Th2 cells in IL-33-mediated type 2 airway inflammation.
bioRxiv
; 2023 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798382
20.
TRAF4 is crucial for ST2+ memory Th2 cell expansion in IL-33-driven airway inflammation.
JCI Insight
; 8(18)2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607012